Laboratory Detection of Enterobacteriaceae That Produce Carbapenemases
نویسندگان
چکیده
منابع مشابه
Laboratory detection of Enterobacteriaceae that produce carbapenemases.
A study was designed to evaluate the modified Hodge test (MHT), Mastdiscs ID inhibitor combination disks (MDI), Rosco Diagnostica Neo-Sensitabs (RDS), metallo-β-lactamase (MBL) Etest, and in-house multiplex PCR for the detection of well-characterized carbapenemase-producing Enterobacteriaceae. One hundred forty-two nonrepeat clinical isolates of carbapenemase-producing Enterobacteriaceae (inclu...
متن کاملDetection of carbapenemases in Enterobacteriaceae by a commercial multiplex PCR.
A commercial multiplex PCR (hyplex SuperBug ID) was tested with a collection of 132 clinical Enterobacteriaceae strains producing different carbapenemases. The sensitivity for the detection of KPC-, VIM-, NDM-, and OXA-48-encoding genes was 100%, whereas two IMP variants were missed.
متن کاملCarbapenemases in Enterobacteriaceae: types and molecular epidemiology.
The most important mechanism of carbapenem resistance in Enterobacteriaceae is the production of carbapenemases, although resistance can also result from the synergistic activity between AmpC-type or (to a lesser extent) extended-spectrum beta-lactamases combined with decreased outer membrane permeability. Three major molecular classes of carbapenemases are recognized: A, B and D. Classes A and...
متن کامل[Laboratory detection of carbapenemase-producing Enterobacteriaceae].
Detection of carbapenemase-producing Enterobacteriaceae in the laboratory requires an exhaustive analysis of the antibiogram and susceptibility to all beta-lactams, the implementation with phenotypic methods of screening as well as confirmatory procedures including the detection of the carbapenem hydrolysis, the inhibition of the enzyme activity with several specific inhibitor compounds and by ...
متن کاملCarbapenemases in Gram-Negative Bacteria: Laboratory Detection and Clinical Significance
1 Clinical Department for Clinical and Molecular Microbiology, University Hospital Center Zagreb, 10000 Zagreb, Croatia 2 Department of Microbiology, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia 3 Department of Microbiology, University Hospital Center Split, 21000 Split, Croatia 4Cantonal Public Health Institute Zenica, 72000 Zenica, Bosnia and Herzegovina 5 Department for Sa...
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 2012
ISSN: 0095-1137
DOI: 10.1128/jcm.02117-12